Scientific dialogue invites discussions and inspires change.

PUBLICATIONS

For a complete list of bibliographic information, see Google Scholar or ORCiD

2021

Endogenous Retroviruses Promote Homeostatic and Inflammatory Responses to the Microbiota

This paper demonstrated that endogenous retroviruses mediate communication between the bacterial microbiota and skin immunity.

Cell


2020

Discovery of Several Thousand Highly Diverse Circular DNA Viruses

This paper systematically identified circular DNA viruses in public sequencing repositories.

eLife


2019

MAIT Cells Are Imprinted by the Microbiota in Early Life and Promote Tissue Repair

This paper demonstrated how early microbial encounters have long-term effects on the composition of the immune system.

Science


2018

Extensive Conservation of Prokaryotic Ribosomal Binding Sites in Known and Novel Picobirnaviruses

This paper repositioned Picobirnaviruses, a viral family previously believed to infect mammals, as one that infects prokaryotes instead

Virology


2017

On the Origin of Reverse Transcriptase- Using CRISPR-Cas Systems and Their Hyperdiverse, Enigmatic Spacer Repertoires

This paper identified RT-based RNA adaptation machinery that joined with CRISPR-Cas immune systems in many, diverse bacterial species.

mBio


2017

Cellular MicroRNA Networks Regulate Host Dependency of Hepatitis C Virus Infection

This paper systematic interrogated how the repertoire of miRNAs impacted HCV life cycle.

Nature Communications


2017

Origins and Challenges of Viral Dark Matter

This review discussed the challenges in identifying viral sequences without relying on classical alignment tools.

Virus Research


2017

VirusSeeker, a Computational Pipeline for Virus Discovery and Virome Composition Analysis

This paper presented a novel tool to discover viruses and characterize viromes.

Virology


2017

Statoviruses, A Novel Taxon of RNA Viruses Present in the Gastrointestinal Tracts of Diverse Mammals

This paper discovered a new genus of RNA viruses found in mammalian stool samples.

Virology


2016

Hyperexpansion of RNA Bacteriophage Diversity

This paper increased the known sequence diversity of RNA bacteriophages from 11 to over 120.

PLoS Biology


2013

Identification of Novel Viruses Using VirusHunter -- an Automated Data Analysis Pipeline

This paper presented a novel tool to discover viruses using deep sequencing data.

PLoS ONE


2013

Hepatitis C Virus Infection Activates an Innate Pathway Involving IKK-α in Lipogenesis and Viral Assembly

This paper showed that HCV uses a novel mechanism to exploit intrinsic innate responses and hijack lipid metabolism.

Nature Medicine


2009

Cutting Edge: Down-Regulation of MHC Class IRelated Chain A on Tumor Cells by IFN-γ-Induced MicroRNA

This paper demonstrated that NKG2D ligands are regulated by an endogenous microRNAs induced by IFN-γ.

The Journal of Immunology


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